Our research 

Bak Probiotic Skincare is developed and manufactured by Danish biotech company Lactobio. The products are based on our own research into new, probiotic bacteria strains as well as a PhD collaboration with Bispebjerg Hospital's dermatological department on skin problems related to Staphylococcus aureus.

In the process of developing Bak Probiotic Skincare, our team of microbiologists, biotechnologists and biochemists have isolated more than 1000 new lactic acid bacteria. Consequently, our patented strain Lactobacillus plantarum LB244R, has been selected for a superior ability to balance the microbiome and for its probiotic, health-promoting properties.

The probiotic lactic acid bacteria in Bak Probiotic Skincare reduce problems of severely dry skin, ensure better skin hydration and effectively soothe and normalise the skin by restoring the natural, bacterial balance of the skin microbiome, which also result in the restoration of the natural immune system.

About Lactobacillus plantarum LB244R

Lactobacillus plantarum is a Gram-positive lactic acid producing bacterium. From birth, Lactobacillus plantarum plays an important role in the development of the skin microbiome. The bacterium is commonly used in fermented foods and as a probiotic dietary supplement. It is listed as GRAS* and as "Qualified Presumption of Safety (QPS)" by the European Food Safety Authority and thus safe for oral intake.

The beneficial probiotic baterium Lactobacillus plantarum LB244R has been isolated by Lactobio ApS and selected from over 1000 newly isolated lactic acid bacteria for its ability to balance the pathogenic bacterium Staphylococcus aureus, which is known to cause dry and itchy skin. LB244R also helps to moisturise the skin and effectively soothe and normalize the skin by restoring the natural, bacterial balance of the skin microbiome, which also result in a restored and well-functioning immune system.

*GRAS (Generally Recognized as Safe) is a term used in US law for substances and products that, based on assessments, are considered safe.

Relevant readings

  • Byrd, Allyson L., Yasmine Belkaid, and Julia A. Segre. 2018. “The Human Skin Microbiome.” Nature Reviews Microbiology 16 (3). Nature Publishing Group: 143–55.
  • Clausen, M. L., S. M. Edslev, P. S. Andersen, K. Clemmensen, K. A. Krogfelt, and T. Agner. 2017. “Staphylococcus Aureus Colonization in Atopic Eczema and Its Association with Filaggrin Gene Mutations.” British Journal of Dermatology 177 (5): 1394–1400.
  • Forum, Helle. 2018. Probiotika: En guide til dine gode bakterier. People ́s Press ISBN 8772004797
  • Lebeer, Sarah, Peter A. Bron, Maria L. Marco, Jan Peter Van Pijkeren, Mary O’Connell Motherway, Colin Hill, Bruno Pot, Stefan Roos, and Todd Klaenhammer. 2018. “Identification of Probiotic Effector Molecules: Present State and Future Perspectives.” Current Opinion in Biotechnology 49 (November 2017). Elsevier Ltd: 217–23.
  • Nakatsuji, Teruaki, Tiffany H. Chen, Aimee M. Two, Kimberly A. Chun, Saisindhu Narala, Raif S. Geha, Tissa R. Hata, and Richard L. Gallo. 2016. “Staphylococcus aureus Exploits Epidermal Barrier Defects in Atopic Dermatitis to Trigger Cytokine Expression.” Journal of Investigative Dermatology 136 (11): 2192–2200.
  • Prince, Tessa, Andrew J. McBain, and Catherine A. O’Neill. 2012. “Lactobacillus Reuteri Protects Epidermal Keratinocytes from Staphylococcus Aureus-Induced Cell Death by Competitive Exclusion.” Applied and Environmental Microbiology 78 (15): 5119–26. doi:10.1128/AEM.00595-12.
  • Rather, Irfan A., Vivek K. Bajpai, Sanjay Kumar, Jeongheui Lim, Woon K. Paek, and Yong Ha Park. 2016. “Probiotics and Atopic Dermatitis: An Overview.” Frontiers in Microbiology 7 (APR): 1–7.
  • Sunada, Yosuke, Syoji Nakamura, and Chiaki Kamei. 2008. “Effect of Lactobacillus acidophilus Strain L-55 on the Development of Atopic Dermatitis-like Skin Lesions in NC/Nga Mice.” International Immunopharmacology 8 (13–14): 1761–66.
  • Totté, J. E.E., W. T. van der Feltz, M. Hennekam, A. van Belkum, E. J. van Zuuren, and S. G.M.A. Pasmans. 2016. “Prevalence and Odds of Staphylococcus Aureus Carriage in Atopic Dermatitis: A Systematic Review and Meta-Analysis.” British Journal of Dermatology 175 (4): 687–95.